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Overview Napoleon and Samantha (1972):

Two young children, who, rather than part with an old pet lion who was once a circus performer, go on a perilous mountain trek to stay with a recluse friend.

Movie details

Title: Napoleon and Samantha

Released: 1972-07-05
Genre: Action, Adventure, Drama, Family
Date: 1972-07-05
Runtime: 92 Minutes
Company: Walt Disney Productions
Language: English
Budget:
Revenue:
Homepage:
Trailer: Video Trailer
Director: Stewart Raffill, Bernard McEveety

Casts of Napoleon and Samantha:
Michael Douglas, Jodie Foster, Johnny Whitaker, Will Geer, Henry Jones, Vito Scotti, Ellen Corby, Mary Wickes, Arch Johnson, Rex Holman

Two runaways and a guardian lion lost in the wilderness... AN INCREDIBLE ADVENTURE!


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SMN2 gene Genetics Home Reference NIH ~ The SMN2 gene provides instructions for making the survival motor neuron SMN protein The SMN protein is found throughout the body with highest levels in the spinal cord This protein is one of a group of proteins called the SMN complex which is important for the maintenance of specialized nerve cells called motor neurons

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Gene SMN1 SMN2 ~ The survival of motor neuron protein SMN is a amino acid RNAbinding protein that can be translated from either the SMN1 or SMN2 genes This protein assembles snRNP complexes that can be used to process mRNA needed to make additional proteins that are necessary for proper growth and function of motor neuron cells

SMN1 Wikipedia ~ SMN1 is the telomeric copy of the gene encoding the SMN protein the centromeric copy is termed SMN2 SMN1 and SMN2 are part of a 500 kb inverted duplication on chromosome 5q13 This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions

SMN1 gene Genetics Home Reference NIH ~ The SMN protein is found throughout the body with highest levels in the spinal cord This protein is one of a group of proteins called the SMN complex which is important for the maintenance of specialized nerve cells called motor neurons These cells are located in the spinal cord and the part of the brain that is connected to the spinal cord

OMIM Entry 600354 SURVIVAL OF MOTOR NEURON 1 SMN1 ~ Lefebvre et al 1995 stated that the human SMN gene has 8 exons however Burglen et al 1996 more fully characterized the SMN gene and showed that it has 9 exons So as not to confuse previously published mutation data Burglen et al 1996 referred to exon 2 as exons 2a and 2b The gene spans about 20 kb The stop codon for the predicted protein occurs in exon 7 and exon 8 is not

Molecular characterization and copy number of SMN1 SMN2 ~ Three types of hybrid SMN genes were found in 6 of the healthy participants Four 19 had a hybrid SMN gene in which exon 8 of SMN2 was converted to exon 8 of SMN1 pattern e in Figure 2 Two 09 had a hybrid SMN gene in which exon 8 of SMN1 was converted to exon 8 of SMN2 pattern h in Figure 2

Spinal Muscular Atrophy Testing via SMN1 SMN2 Copy ~ Diagnostic Confirmation SMN1 gene dosage analysis will confirm diagnosis for around 95 of patients with SMA those with homozygous deletions of SMN1 00 In patients with one copy of SMN1 in whom there is a high suspicion of SMA SMN1 sequencing should be considered to look for a small variant or deletion Because the SMN2 gene produces a small amount of SMN protein increased copy number

SMN1 Survival motor neuron protein Homo sapiens Human ~ The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins snRNPs the building blocks of the spliceosome Thereby plays an important role in the splicing of cellular premRNAs Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the


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